Neutrophilic dermatosis of the hands and erythema nodusum in a patient with acute myeloid leukemia




Lucía Palmero, Servicio de Dermatología, Hospital Privado Universitario de Córdoba, Universidad Católica de Córdoba, Córdoba, Argentina
Melisa V. Corball, Servicio de Dermatología, Hospital Privado Universitario de Córdoba, Universidad Católica de Córdoba, Córdoba, Argentina
Iliana S. Garay, Servicio de Dermatología, Hospital Privado Universitario de Córdoba, Universidad Católica de Córdoba, Córdoba, Argentina
Enrique Valente, Servicio de Dermatología, Hospital Privado Universitario de Córdoba, Universidad Católica de Córdoba, Córdoba, Argentina
Alejandro Ruiz-Lascano, Servicio de Dermatología, Hospital Privado Universitario de Córdoba, Universidad Católica de Córdoba, Córdoba, Argentina
María Kurpis, Servicio de Anatomía Patológica. Hospital Privado Universitario de Córdoba, Universidad Católica de Córdoba, Córdoba, Argentina


Neutrophilic dermatosis of the hands is considered an acral localized variant of Sweet Syndrome, mainly associated with hematological diseases. Erythema nodosum is the most common type of acute panniculitis. It is a septal panniculitis related to a delayed hypersensitivity phenomenon. It can be idiopathic or secondary to a wide variety of diseases, including hematological ones. We report the case of an 83 years old patient with Neutrophilic dermatosis of the hands and erythema nodosum in the context of a recent diagnosis of acute myeloid leukemia, who presented a good response to corticosteroid treatment and fast resolution of the skin lesions. We highlight this association barely reported in the literature between these two entities and with the underlying hematological disease.



Keywords: Hand neutrophilic dermatosis. Sweet syndrome. Erythema nodosum. Myeloid leukemia.