Nail lichen planus: case report with satisfactory response to topical treatment under occlusion




Cristina B. Adrián-Rivera, Consulta Clínica de Dermatología, Instituto Dermatológico Dominicano y Cirugía de Piel Dr. Huberto Bogaert Díaz, Santo Domingo, República Dominicana
Reina de los Santos, Consulta Clínica de Dermatología, Instituto Dermatológico Dominicano y Cirugía de Piel Dr. Huberto Bogaert Díaz, Santo Domingo, República Dominicana
Raisa Acosta, Consulta Clínica de Dermatología, Instituto Dermatológico Dominicano y Cirugía de Piel Dr. Huberto Bogaert Díaz, Santo Domingo, República Dominicana
Amelia Navarro, Consulta Clínica de Dermatología, Instituto Dermatológico Dominicano y Cirugía de Piel Dr. Huberto Bogaert Díaz, Santo Domingo, República Dominicana
Camila Carpio, Consulta Clínica de Dermatología, Instituto Dermatológico Dominicano y Cirugía de Piel Dr. Huberto Bogaert Díaz, Santo Domingo, República Dominicana


Nail lichen planus (NLP) is an aggressive, disfiguring variant of lichen planus, with suboptimal therapeutic response. We present a case of a 44-year-old female, who presents a 7-month-old history of onycholysis and onychodystrophy. Histopathology reports lichenoid dermatitis, confirming NLP diagnosis. Topical treatment with steroids under occlusion was initiated for twelve weeks, continuing with topical tacrolimus, observing a near total improvement at 20 weeks. NLP’s clinical aggressiveness makes prompt diagnosis and treatment a necessity to minimize damage. Topical treatment under occlusion is a simple and accessible treatment option to be considered.



Keywords: Nail lichen planus. Topical therapy. Steroids. Tacrolimus. Occlusive treatment.